The wg maq125 and wg maq30 data sets are now supplied as supplementary data tracks within the nexus copy number software. Technical matters about data analysis and software operation, reporting, administration, maintenancepatching, etc. The platform specific software cnv call set for the first replicate of the. Application of nexus copy number software for cnv detection and analysis. The cnv detection tool of nextgene software includes a sophisticated coveragebased algorithm developed for ngs sequencing data from instruments such as illumina, and ion torrent sequencing platforms. The agilent community is the preferred place for users of agilent products to connect, collaborate, and share insights. These are evaluated using companyrecommended software tools, as well. Multi analysis software for molecular cytogenetics agilent. See the company profile for agilent technologies, inc. Access suredesign, a free online customization tool with 29 million probes detect exon level copy number changes on arrays no minimum orders or premium price requirements. Ols based cgh microarrays accurately detect copy number variations at. Surecall analysis software that detects genomewide copy number changes.
Application of nexus copy number software for cnv detection and. Softgenetics software powertools for genetic analysis. Agilent has predesigned thousands of wg maq assays with an average test amplicon spacing of respectively 125 and 30 kb. Agilent cytogenomics software provides advanced data analysis tools for. Affymetrix, agilent and illuminaoffer solutions for snp genotyping for. Research solution includes arrays, reagents, and analysis software for the detection of a broad. Changes in the copy number of chromosomal dna segments. Copy number aberration calls are determined entirely by nonsnp oligonucleotides maximizing signaltonoise ratio. A including business summary, industrysector information, number of employees, business summary, corporate governance, key executives and. Performance assessment of copy number microarray platforms. All members are welcome to contribute and comment on all items, including questions, blog posts, screenshots, etc. Agilent cytogenomics software provides advanced data analysis tools for cytogeneticists. Agilents acgh platform features a combination of optimal probe length and probe coverage to accurately detect small differences in copy number changes.
The algorithms in the nexus software are not optimized to analyze agilent snp data from cancer samples. It is used in combination with roi maq or wg maq assays in researchonly applications. Genomewide copy number is important when analyzing solid tumors. Powered with the goldstandard cnv calling algorithm, nexus copy number software derives copy number and baf from a variety of ngs data wes, wgs.
Download scientific diagram summary of copy number analysis cytogenomics v2. Estimating copy number from log ratios biodiscovery. A maintenance, diagnostics and calibration software toolset for agilent uhplc and ce instruments non agilent instrument support for openlab cds chemstation edition software vendor. Nimblegen and agilent platforms outperformed illumina and affymetrix.
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